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PNP Antikörper (AA 1-289)

NP Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6145854
  • Target Alle PNP (NP) Antikörper anzeigen
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Bindungsspezifität
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-289
    Reaktivität
    • 36
    • 12
    • 11
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 4
    • 1
    • 1
    Kaninchen
    Klonalität
    • 41
    • 3
    Polyklonal
    Konjugat
    • 25
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PNP Antikörper ist unkonjugiert
    Applikation
    • 24
    • 17
    • 12
    • 9
    • 9
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    Sequenz
    MENGYTYEDY KNTAEWLLSH TKHRPQVAII CGSGLGGLTD KLTQAQIFDY GEIPNFPRST VPGHAGRLVF GFLNGRACVM MQGRFHMYEG YPLWKVTFPV RVFHLLGVDT LVVTNAAGGL NPKFEVGDIM LIRDHINLPG FSGQNPLRGP NDERFGDRFP AMSDAYDRTM RQRALSTWKQ MGEQRELQEG TYVMVAGPSF ETVAECRVLQ KLGADAVGMS TVPEVIVARH CGLRVFGFSL ITNKVIMDYE SLEKANHEEV LAAGKQAAQK LEQFVSILMA SIPLPDKAS
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human PNP (NP_000261.2).
    Isotyp
    IgG
    Top Product
    Discover our top product NP Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IP,1:50 - 1:100
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    PNP (NP) (Nucleoside Phosphorylase (NP))
    Andere Bezeichnung
    PNP (NP Produkte)
    Synonyme
    NP antikoerper, PRO1837 antikoerper, PUNP antikoerper, Np antikoerper, AL024301 antikoerper, AU015798 antikoerper, Np-1 antikoerper, Np-2 antikoerper, Pnp1 antikoerper, purine nucleoside phosphorylase antikoerper, purine-nucleoside phosphorylase antikoerper, PNP antikoerper, Pnp antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.,PNP,NP,PRO1837,PUNP,Neuroscience,Neurodegenerative Diseases,PNP
    Molekulargewicht
    32 kDa
    Gen-ID
    4860
    UniProt
    P00491
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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