PDE6A Antikörper (AA 656-860)

Produktnummer ABIN6145361

Produktdetails anti-PDE6A Antikörper

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Bindungsspezifität: AA 656-860

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: EHAIHMMDIA IIATDLALYF KKRTMFQKIV DQSKTYESEQ EWTQYMMLEQ TRKEIVMAMM MTACDLSAIT KPWEVQSQVA LLVAAEFWEQ GDLERTVLQQ NPIPMMDRNK ADELPKLQVG FIDFVCTFVY KEFSRFHEEI TPMLDGITNN RKEWKALADE YDAKMKVQEE KKQKQQSAKS AAAGNQPGGN PSPGGATTSK SCCIQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 656-860 of human PDE6A (NP_000431.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PDE6A

Target: PDE6A (phosphodiesterase 6A, CGMP-Specific, Rod, alpha (PDE6A))

Andere Bezeichnung: PDE6A (PDE6A Produkte)

Synonyme: si:bz1d10.3 antikoerper, si:rp71-1d10.3 antikoerper, CGPR-A antikoerper, PDEA antikoerper, RP43 antikoerper, Pdea antikoerper, nmf282 antikoerper, phosphodiesterase 6A, cGMP-specific, rod, alpha antikoerper, phosphodiesterase 6A antikoerper, pde6a antikoerper, PDE6A antikoerper, Pde6a antikoerper

Hintergrund: This gene encodes the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.,PDE6A,CGPR-A,PDEA,RP43,Signal Transduction,Neuroscience,PDE6A

Molekulargewicht: 99 kDa

Gen-ID: 5145

UniProt: P16499

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction