NPR1 Antikörper (AA 260-470)

Produktnummer ABIN6144783

Produktdetails anti-NPR1 Antikörper

Target: NPR1 (Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1))

Bindungsspezifität: AA 260-470

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EAGLCGEDYV FFHLDIFGQS LQGGQGPAPR RPWERGDGQD VSARQAFQAA KIITYKDPDN PEYLEFLKQL KHLAYEQFNF TMEDGLVNTI PASFHDGLLL YIQAVTETLA HGGTVTDGEN ITQRMWNRSF QGVTGYLKID SSGDRETDFS LWDMDPENGA FRVVLNYNGT SQELVAVSGR KLNWPLGYPP PDIPKCGFDN EDPACNQDHL S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 260-470 of human NPR1 (NP_000897.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NPR1

Target: NPR1 (Natriuretic Peptide Receptor A/guanylate Cyclase A (Atrionatriuretic Peptide Receptor A) (NPR1))

Andere Bezeichnung: NPR1 (NPR1 Produkte)

Synonyme: ANPRA antikoerper, ANPa antikoerper, GUC2A antikoerper, GUCY2A antikoerper, NPRA antikoerper, Anpra antikoerper, Gca antikoerper, NPR-A antikoerper, Npra antikoerper, sGC antikoerper, si:dkey-27c15.1 antikoerper, AI893888 antikoerper, GC-A antikoerper, Pndr antikoerper, ARABIDOPSIS NONEXPRESSER OF PR GENES 1 antikoerper, ATNPR1 antikoerper, F15H21.6 antikoerper, F15H21_6 antikoerper, NIM1 antikoerper, NON-INDUCIBLE IMMUNITY 1 antikoerper, NONEXPRESSER OF PR GENES 1 antikoerper, REGULATORY PROTEIN NPR1 antikoerper, SAI1 antikoerper, SALICYLIC ACID INSENSITIVE 1 antikoerper, natriuretic peptide receptor 1 antikoerper, natriuretic peptide receptor 1a antikoerper, regulatory protein (NPR1) antikoerper, NPR1 antikoerper, Npr1 antikoerper, npr1a antikoerper

Hintergrund: Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms (Garbers and Lowe, 1994 [PubMed 7982997]). The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides, they are also referred to as atrial natriuretic peptide receptor A (NPR1) and type B (NPR2, MIM 108961). Also see NPR3 (MIM 108962), which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides (ANP (MIM 108780) and BNP (MIM 600295), respectively).[supplied by OMIM, May 2009],NPR1,ANPRA,ANPa,GUC2A,GUCY2A,NPRA,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cardiovascular,Angiogenesis,Blood,Blood Pressure regulation,NPR1

Molekulargewicht: 118 kDa

Gen-ID: 4881

UniProt: P16066