Factor VIII Antikörper
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- Target Alle Factor VIII (F8) Antikörper anzeigen
- Factor VIII (F8) (Coagulation Factor VIII (F8))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Factor VIII Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody recognizes full-length Human Factor VIII (F8). Does not cross-react with von Willebrand factor.
- Aufreinigung
- Protein G chromatography
- Immunogen
- F8 antibody was raised against purified human Factor VIII.
- Klon
- N-a
- Isotyp
- IgG1
- Top Product
- Discover our top product F8 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.73 mg/mL
- Buffer
- PBS, pH 7.4
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store the antibody at -20 °C to -70 °C.
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- Target
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- Abstract
- F8 Produkte
- Synonyme
- fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper
- Hintergrund
- This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.Synonyms: AHF, Antihemophilic factor, F8C, Procoagulant component
- Gen-ID
- 2157
- NCBI Accession
- NP_000123
- UniProt
- P00451
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