MYH7 Antikörper (AA 1766-1935)

Produktnummer ABIN6144239

Produktdetails anti-MYH7 Antikörper

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Bindungsspezifität: AA 1766-1935

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYH7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: AEELKKEQDT SAHLERMKKN MEQTIKDLQH RLDEAEQIAL KGGKKQLQKL EARVRELENE LEAEQKRNAE SVKGMRKSER RIKELTYQTE EDRKNLLRLQ DLVDKLQLKV KAYKRQAEEA EEQANTNLSK FRKVQHELDE AEERADIAES QVNKLRAKSR DIGTKGLNEE

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1766-1935 of human MYH7/beta-MHC (NP_000248.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MYH7 Antikörper (ABIN6144239)

Kumar, Wang, Liu, Ding, Dong, Zheng, Ye, Liu: "Hypoxia-Induced Mitogenic Factor Promotes Cardiac Hypertrophy via Calcium-Dependent and Hypoxia-Inducible Factor-1α Mechanisms." in: Hypertension (Dallas, Tex. : 1979), Vol. 72, Issue 2, pp. 331-342, (2018) (PubMed).

Fan, Long, Yan, Wang, Shi, Bao, Hu, Li, Chen, Zheng, Yan: "Dietary leucine supplementation alters energy metabolism and induces slow-to-fast transitions in longissimus dorsi muscle of weanling piglets." in: The British journal of nutrition, Vol. 117, Issue 9, pp. 1222-1234, (2017) (PubMed).

Details zu MYH7

Target: MYH7 (Myosin Heavy Chain 7, Cardiac Muscle, beta (MYH7))

Andere Bezeichnung: MYH7 (MYH7 Produkte)

Synonyme: CMD1S antikoerper, CMH1 antikoerper, MPD1 antikoerper, MYHCB antikoerper, SPMD antikoerper, SPMM antikoerper, Myhcb antikoerper, AMHC1 antikoerper, myosin antikoerper, myosin-7 antikoerper, B-MHC antikoerper, MyHC-I antikoerper, Myhc-b antikoerper, beta-MHC antikoerper, myosin heavy chain 7 antikoerper, myosin, heavy chain 7, cardiac muscle, beta antikoerper, myosin, heavy polypeptide 7, cardiac muscle, beta antikoerper, MYH7 antikoerper, Myh7 antikoerper

Hintergrund: Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle. Its expression is also altered during thyroid hormone depletion and hemodynamic overloading. Mutations in this gene are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.,MYH7,CMD1S,CMH1,MPD1,MYHCB,SPMD,SPMM,myosin-7,MYH7,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYH7

Molekulargewicht: 223 kDa

Gen-ID: 4625

UniProt: P12883