MARK1 Antikörper (AA 560-700)

Produktnummer ABIN6143561

Produktdetails anti-MARK1 Antikörper

Target: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Bindungsspezifität: AA 560-700

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: HPIKVTLPTI KDGSEAYRPG TTQRVPAASP SAHSISTATP DRTRFPRGSS SRSTFHGEQL RERRSVAYNG PPASPSHETG AFAHARRGTS TGIISKITSK FVRRDPSEGE ASGRTDTSRS TSGEPKERDK EEGKDSKPRS L

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 560-700 of human MARK1 (NP_061120.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MARK1

Target: MARK1 (MAP/microtubule Affinity-Regulating Kinase 1 (MARK1))

Andere Bezeichnung: MARK1 (MARK1 Produkte)

Synonyme: MGC80341 antikoerper, MARK1 antikoerper, AW491150 antikoerper, B930025N23Rik antikoerper, Emk3 antikoerper, Par-1c antikoerper, mKIAA1477 antikoerper, mPar-1c antikoerper, MARK antikoerper, Par1c antikoerper, MAP/microtubule affinity-regulating kinase 1 S homeolog antikoerper, microtubule affinity regulating kinase 1 antikoerper, MAP/microtubule affinity-regulating kinase 1 antikoerper, MAP/microtubule affinity regulating kinase 1 antikoerper, mark1.S antikoerper, MARK1 antikoerper, mark1 antikoerper, Mark1 antikoerper

Hintergrund: Serine/threonine-protein kinase. Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3.,MARK1,MARK,Par-1c,Par1c,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,MARK1

Molekulargewicht: 72 kDa/84 kDa/89 kDa

Gen-ID: 4139

UniProt: Q9P0L2

Pathways: SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion