IREB2 Antikörper (AA 1-250)

Produktnummer ABIN6142524

Produktdetails anti-IREB2 Antikörper

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IREB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MDAPKAGYAF EYLIETLNDS SHKKFFDVSK LGTKYDVLPY SIRVLLEAAV RNCDGFLMKK EDVMNILDWK TKQSNVEVPF FPARVLLQDF TGIPAMVDFA AMREAVKTLG GDPEKVHPAC PTDLTVDHSL QIDFSKCAIQ NAPNPGGGDL QKAGKLSPLK VQPKKLPCRG QTTCRGSCDS GELGRNSGTF SSQIENTPIL CPFHLQPVPE PETVLKNQEV EFGRNRERLQ FFKWSSRVFK NVAVIPPGTG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human IREB2 (NP_004127.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:20 - 1:50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IREB2

Target: IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))

Andere Bezeichnung: IREB2 (IREB2 Produkte)

Synonyme: IREB2 antikoerper, im:7153062 antikoerper, DKFZp468N047 antikoerper, D9Ertd85e antikoerper, Irp2 antikoerper, ACO3 antikoerper, IRP2 antikoerper, IRP2AD antikoerper, IREBP2 antikoerper, iron responsive element binding protein 2 antikoerper, iron-responsive element binding protein 2 antikoerper, iron responsive element binding protein 2 L homeolog antikoerper, IREB2 antikoerper, ireb2 antikoerper, Ireb2 antikoerper, ireb2.L antikoerper

Hintergrund: RNA-binding protein that binds to iron-responsive elements (IRES, which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.,IREB2,ACO3,IRP2,IRP2AD,Endocrine & Metabolism,Cardiovascular,Hypoxia,Hypoxia-Regulated,IREB2

Molekulargewicht: 37 kDa/105 kDa

Gen-ID: 3658

UniProt: P48200

Pathways: Transition Metal Ion Homeostasis