Metabotropic Glutamate Receptor 4 Antikörper (AA 33-290)

Produktnummer ABIN6141425

Produktdetails anti-Metabotropic Glutamate Receptor 4 Antikörper

Target: Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))

Bindungsspezifität: AA 33-290

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KPKGHPHMNS IRIDGDITLG GLFPVHGRGS EGKPCGELKK EKGIHRLEAM LFALDRINND PDLLPNITLG ARILDTCSRD THALEQSLTF VQALIEKDGT EVRCGSGGPP IITKPERVVG VIGASGSSVS IMVANILRLF KIPQISYAST APDLSDNSRY DFFSRVVPSD TYQAQAMVDI VRALKWNYVS TVASEGSYGE SGVEAFIQKS REDGGVCIAQ SVKIPREPKA GEFDKIIRRL LETSNARAVI IFANEDDI

Kreuzreaktivität: Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 33-290 of human GRM4 (NP_000832.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Metabotropic Glutamate Receptor 4

Target: Metabotropic Glutamate Receptor 4 (GRM4) (Glutamate Receptor, Metabotropic 4 (GRM4))

Andere Bezeichnung: GRM4 (GRM4 Produkte)

Synonyme: GPRC1D antikoerper, MGLUR4 antikoerper, mGlu4 antikoerper, Gprc1d antikoerper, mGluR4 antikoerper, glutamate metabotropic receptor 4 antikoerper, glutamate receptor, metabotropic 4 antikoerper, GRM4 antikoerper, Grm4 antikoerper

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.,GRM4,GPRC1D,MGLUR4,mGlu4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Neuroscience,GRM4

Molekulargewicht: 83 kDa/86 kDa/87 kDa/88 kDa/101 kDa

Gen-ID: 2914

UniProt: Q14833