DUSP9 Antikörper

Produktnummer ABIN6139880

Produktdetails anti-DUSP9 Antikörper

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human DUSP9

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:20 - 1:200,IF,1:20 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP9

Target: DUSP9 (Dual Specificity Phosphatase 9 (DUSP9))

Andere Bezeichnung: DUSP9 (DUSP9 Produkte)

Synonyme: MKP-4 antikoerper, MKP4 antikoerper, Dusp4 antikoerper, Mpk4 antikoerper, Pyst3 antikoerper, DUSP9 antikoerper, dual specificity phosphatase 9 antikoerper, DUSP9 antikoerper, Dusp9 antikoerper

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.,DUSP9,MKP-4,MKP4,Signal Transduction,DUSP9

Molekulargewicht: 41 kDa

Gen-ID: 1852

UniProt: Q99956