CYP46A1 Antikörper (AA 24-280)

Produktnummer ABIN6139358

Produktdetails anti-CYP46A1 Antikörper

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Bindungsspezifität: AA 24-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP46A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: HRARSRYEHI PGPPRPSFLL GHLPCFWKKD EVGGRVLQDV FLDWAKKYGP VVRVNVFHKT SVIVTSPESV KKFLMSTKYN KDSKMYRALQ TVFGERLFGQ GLVSECNYER WHKQRRVIDL AFSRSSLVSL METFNEKAEQ LVEILEAKAD GQTPVSMQDM LTYTAMDILA KAAFGMETSM LLGAQKPLSQ AVKLMLEGIT ASRNTLAKFL PGKRKQLREV RESIRFLRQV GRDWVQRRRE ALKRGEEVPA DILTQIL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-280 of human CYP46A1 (NP_006659.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP46A1

Target: CYP46A1 (Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))

Andere Bezeichnung: CYP46A1 (CYP46A1 Produkte)

Synonyme: CP46 antikoerper, CYP46 antikoerper, CYP46A1 antikoerper, zgc:109896 antikoerper, MGC147389 antikoerper, Cyp46 antikoerper, cytochrome P450 family 46 subfamily A member 1 antikoerper, cytochrome P450 family 46 subfamily A member 1 L homeolog antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 antikoerper, cytochrome P450, family 46 antikoerper, cytochrome P450 46A1 antikoerper, cytochrome P450, family 46, subfamily a, polypeptide 1 antikoerper, cholesterol 24-hydroxylase antikoerper, cytochrome P450, family 46, subfamily A, polypeptide 1 antikoerper, CYP46A1 antikoerper, cyp46a1.L antikoerper, cyp46a1.1 antikoerper, cyp46a1 antikoerper, PTRG_08343 antikoerper, PTRG_09667 antikoerper, Cyp46a1 antikoerper, Sgly_1093 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism.,CYP46A1,CP46,CYP46,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Drug metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CYP46A1

Molekulargewicht: 38 kDa/45 kDa/56 kDa

Gen-ID: 10858

UniProt: Q9Y6A2