CYP11B1 Antikörper (AA 234-503)

Produktnummer ABIN6139312

Produktdetails anti-CYP11B1 Antikörper

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Bindungsspezifität: AA 234-503

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP11B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVQLMFMPRS LSRWTSPKVW KEHFEAWDCI FQYGDNCIQK IYQELAFSRP QQYTSIVAEL LLNAELSPDA IKANSMELTA GSVDTTVFPL LMTLFELARN PNVQQALRQE SLAAAASISE HPQKATTELP LLRAALKETL RLYPVGLFLE RVASSDLVLQ NYHIPAGTLV RVFLYSLGRN PALFPRPERY NPQRWLDIRG SGRNFYHVPF GFGMRQCLGR RLAEAEMLLL LHHVLKHLQV ETLTQEDIKM VYSFILRPSM FPLLTFRAIN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 234-503 of human CYP11B1 (NP_000488.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP11B1

Target: CYP11B1 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 1 (CYP11B1))

Andere Bezeichnung: CYP11B1 (CYP11B1 Produkte)

Synonyme: CPN1 antikoerper, CYP11B antikoerper, FHI antikoerper, P450C11 antikoerper, AA389061 antikoerper, Cyp11b antikoerper, Cyp11b-1 antikoerper, Cp11ba antikoerper, RATCP11BA antikoerper, P450c11 antikoerper, cytochrome P450, family 11, subfamily B, polypeptide 1 antikoerper, cytochrome P450 family 11 subfamily B member 1 antikoerper, cytochrome P450, family 11, subfamily b, polypeptide 1 antikoerper, cytochrome P450, subfamily XI B, polypeptide 1 antikoerper, CYP11B1 antikoerper, Cyp11b1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and is involved in the conversion of progesterone to cortisol in the adrenal cortex. Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency. Transcript variants encoding different isoforms have been noted for this gene.,CYP11B1,CPN1,CYP11B,FHI,P450C11,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Mitochondrial markers,Lipid Metabolism,Cytochromes,Lipases,Cardiovascular,Lipids,CYP11B1

Molekulargewicht: 49 kDa/57 kDa

Gen-ID: 1584

UniProt: P15538

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Carbohydrate Homeostasis