CPT1A Antikörper (AA 497-756)
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- Target Alle CPT1A Antikörper anzeigen
- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
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Bindungsspezifität
- AA 497-756
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CPT1A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)
- Sequenz
- GYAEDGHCKG DINPNIPYPT RLQWDIPGEC QEVIETSLNT ANLLANDVDF HSFPFVAFGK GIIKKCRTSP DAFVQLALQL AHYKDMGKFC LTYEASMTRL FREGRTETVR SCTTESCDFV RAMVDPAQTV EQRLKLFKLA SEKHQHMYRL AMTGSGIDRH LFCLYVVSKY LAVESPFLKE VLSEPWRLST SQTPQQQVEL FDLENNPEYV SSGGGFGPVA DDGYGVSYIL VGENLINFHI SSKFSCPETG IISQGPSSDT
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 497-756 of human CPT1A (NP_001027017.1).
- Isotyp
- IgG
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:100
- Kommentare
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HIGH QUALITY
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
: "Oroxylin A suppresses the development and growth of colorectal cancer through reprogram of HIF1α-modulated fatty acid metabolism." in: Cell death & disease, Vol. 8, Issue 6, pp. e2865, (2018) (PubMed).
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Regulation of AMPK-related glycolipid metabolism imbalances redox homeostasis and inhibits anchorage independent growth in human breast cancer cells." in: Redox biology, Vol. 17, pp. 180-191, (2018) (PubMed).
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- Target
- CPT1A (Carnitine Palmitoyltransferase 1A (Liver) (CPT1A))
- Andere Bezeichnung
- CPT1A (CPT1A Produkte)
- Synonyme
- MGC53498 antikoerper, CPT1 antikoerper, CPT1-L antikoerper, L-CPT1 antikoerper, L-CPTI antikoerper, si:dkey-56p7.8 antikoerper, C730027G07 antikoerper, CPTI antikoerper, Cpt1 antikoerper, CPT-Ia antikoerper, carnitine palmitoyltransferase 1A (liver) L homeolog antikoerper, carnitine palmitoyltransferase 1A antikoerper, carnitine palmitoyltransferase 1A (liver) antikoerper, carnitine palmitoyltransferase 1Aa (liver) antikoerper, carnitine palmitoyltransferase 1a, liver antikoerper, cpt1a.L antikoerper, CPT1A antikoerper, cpt1a antikoerper, cpt1aa antikoerper, Cpt1a antikoerper
- Hintergrund
- The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane and is detergent-stable), together with a carnitine-acylcarnitine translocase. CPT I is the key enzyme in the carnitine-dependent transport across the mitochondrial inner membrane and its deficiency results in a decreased rate of fatty acid beta-oxidation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,CPT1A,CPT1,CPT1-L,L-CPT1,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Lipid Metabolism,AMPK Signaling Pathway,Endocrine and metabolic diseases,Obesity,Cardiovascular,Lipids,Fatty Acids,CPT1A
- Molekulargewicht
- 86 kDa/88 kDa
- Gen-ID
- 1374
- UniProt
- P50416
- Pathways
- AMPK Signaling, Regulation of Lipid Metabolism by PPARalpha, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
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