COL4A1 Antikörper (AA 1445-1669)

Produktnummer ABIN6138841

Produktdetails anti-COL4A1 Antikörper

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Bindungsspezifität: AA 1445-1669

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COL4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GFLVTRHSQT IDDPQCPSGT KILYHGYSLL YVQGNERAHG QDLGTAGSCL RKFSTMPFLF CNINNVCNFA SRNDYSYWLS TPEPMPMSMA PITGENIRPF ISRCAVCEAP AMVMAVHSQT IQIPPCPSGW SSLWIGYSFV MHTSAGAEGS GQALASPGSC LEEFRSAPFI ECHGRGTCNY YANAYSFWLA TIERSEMFKK PTPSTLKAGE LRTHVSRCQV CMRRT

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1445-1669 of human COL4A1 (NP_001836.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COL4A1

Target: COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))

Andere Bezeichnung: COL4A1 (COL4A1 Produkte)

Synonyme: col4a1 antikoerper, wu:fc02g11 antikoerper, HANAC antikoerper, ICH antikoerper, POREN1 antikoerper, arresten antikoerper, Bru antikoerper, Col4a-1 antikoerper, Del(8)44H antikoerper, Raw antikoerper, Svc antikoerper, collagen, type IV, alpha 5 (Alport syndrome) antikoerper, collagen type IV alpha 1 chain antikoerper, collagen, type IV, alpha 1 antikoerper, col4a5 antikoerper, COL4A1 antikoerper, Col4a1 antikoerper

Hintergrund: This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants.,COL4A1,BSVD,RATOR,Stem Cells,COL4A1

Molekulargewicht: 127 kDa/160 kDa

Gen-ID: 1282

UniProt: P02462

Pathways: Skeletal Muscle Fiber Development, Growth Factor Binding