CIDEA Antikörper (AA 20-219)

Produktnummer ABIN6138621

Produktdetails anti-CIDEA Antikörper

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Bindungsspezifität: AA 20-219

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CIDEA Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Sequenz: SQTKRVLFTP LMHPARPFRV SNHDRSSRRG VMASSLQELI SKTLDALVIA TGLVTLVLEE DGTVVDTEEF FQTLGDNTHF MILEKGQKWM PGSQHVPTCS PPKRSGIARV TFDLYRLNPK DFIGCLNVKA TMYEMYSVSY DIRCTGLKGL LRSLLRFLSY SAQVTGQFLI YLGTYMLRVL DDKEERPSLR SQAKGRFTCG

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-219 of human CIDEA (NP_001270.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CIDEA

Target: CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))

Andere Bezeichnung: CIDEA (CIDEA Produkte)

Synonyme: CIDE-A antikoerper, AW212747 antikoerper, CIDEA antikoerper, cide-a antikoerper, MGC89985 antikoerper, cell death-inducing DFFA-like effector a antikoerper, cell death-inducing DNA fragmentation factor, alpha subunit-like effector A antikoerper, cell death-inducing DFFA-like effector a L homeolog antikoerper, CIDEA antikoerper, Cidea antikoerper, cidea antikoerper, cidea.L antikoerper

Hintergrund: This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.,CIDEA,CIDE-A,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Endocrine & Metabolism,Cardiovascular,Heart,Lipids,Fatty Acids,CIDEA

Molekulargewicht: 24 kDa

Gen-ID: 1149

UniProt: O60543