CD5L Antikörper (AA 20-347)

Produktnummer ABIN6138212

Produktdetails anti-CD5L Antikörper

Target: CD5L (CD5 Molecule-Like (CD5L))

Bindungsspezifität: AA 20-347

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SPSGVRLVGG LHRCEGRVEV EQKGQWGTVC DDGWDIKDVA VLCRELGCGA ASGTPSGILY EPPAEKEQKV LIQSVSCTGT EDTLAQCEQE EVYDCSHDED AGASCENPES SFSPVPEGVR LADGPGHCKG RVEVKHQNQW YTVCQTGWSL RAAKVVCRQL GCGRAVLTQK RCNKHAYGRK PIWLSQMSCS GREATLQDCP SGPWGKNTCN HDEDTWVECE DPFDLRLVGG DNLCSGRLEV LHKGVWGSVC DDNWGEKEDQ VVCKQLGCGK SLSPSFRDRK CYGPGVGRIW LDNVRCSGEE QSLEQCQHRF WGFHDCTHQE DVAVICSG

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-347 of human CD5L (NP_005885.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD5L

Target: CD5L (CD5 Molecule-Like (CD5L))

Andere Bezeichnung: CD5L (CD5L Produkte)

Synonyme: AIM antikoerper, API6 antikoerper, PRO229 antikoerper, SP-ALPHA antikoerper, Spalpha antikoerper, 1/6 antikoerper, AAC-11 antikoerper, AI047839 antikoerper, Api6 antikoerper, CT2 antikoerper, Pdp antikoerper, Sp-alpha antikoerper, CD5L antikoerper, CD5 molecule like antikoerper, CD5 antigen-like antikoerper, Cd5 molecule-like antikoerper, CD5 molecule-like antikoerper, scavenger receptor cysteine-rich domain superfamily protein-like antikoerper, CD5L antikoerper, Cd5l antikoerper, LOC100375137 antikoerper

Hintergrund: CD5L (CD5 antigen-like), also known as Sp alpha and AIM, is a 50 kDa secreted glycoprotein that belongs to the SRCR (scavenger receptor cysteine rich) group B family of proteins. CD5L is up-regulated in macrophages at inflammatory sites. It sustains inflammatory reactions by both increasing the phagocytic capacity of macrophages and impeding the apoptosis of local macrophages, NK cells, and T cells. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. In the thymic cortex, CD5L protects cortical CD4+CD8+thymocytes from apoptosis. CD5L circulates in the serum in complex with IgM.,CD5L,AIM,API6,CT-2,PRO229,SP-ALPHA,Spalpha,hAIM,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD5L

Molekulargewicht: 38 kDa

Gen-ID: 922

UniProt: O43866