CALCOCO1 Antikörper (AA 462-691)

Produktnummer ABIN6137858

Produktdetails anti-CALCOCO1 Antikörper

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Bindungsspezifität: AA 462-691

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CALCOCO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LVQLSESKRE LTELRSALRV LQKEKEQLQE EKQELLEYMR KLEARLEKVA DEKWNEDATT EDEEAAVGLS CPAALTDSED ESPEDMRLPP YGLCERGDPG SSPAGPREAS PLVVISQPAP ISPHLSGPAE DSSSDSEAED EKSVLMAAVQ SGGEEANLLL PELGSAFYDM ASGFTVGTLS ETSTGGPATP TWKECPICKE RFPAESDKDA LEDHMDGHFF FSTQDPFTFE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 462-691 of human CALCOCO1 (NP_065949.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CALCOCO1

Target: CALCOCO1 (Calcium Binding and Coiled-Coil Domain 1 (CALCOCO1))

Andere Bezeichnung: CALCOCO1 (CALCOCO1 Produkte)

Synonyme: Cocoa antikoerper, calphoglin antikoerper, fa11a10 antikoerper, wu:fa11a10 antikoerper, CALCOCO1 antikoerper, Xdsg antikoerper, cocoa antikoerper, dsgc antikoerper, pp13275 antikoerper, 1810009B06Rik antikoerper, Gcap11 antikoerper, mKIAA1536 antikoerper, calcium binding and coiled-coil domain 1 antikoerper, calcium binding and coiled-coil domain 1a antikoerper, calcium binding and coiled-coil domain 1 S homeolog antikoerper, calcium binding and coiled-coil domain 1 L homeolog antikoerper, calcium binding and coiled coil domain 1 antikoerper, CALCOCO1 antikoerper, calcoco1a antikoerper, calcoco1.S antikoerper, calcoco1.L antikoerper, Calcoco1 antikoerper

Hintergrund: Functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR. Recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS domain of transcription factors or coactivators, such as NCOA2. During ER-activation acts synergistically in combination with other NCOA2-binding proteins, such as EP300, CREBBP and CARM1. Involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. Functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions (By similarity. In association with CCAR1 enhances GATA1- and MED1-mediated transcriptional activation from the gamma-globin promoter during erythroid differentiation of K562 erythroleukemia cells.,CALCOCO1,Cocoa,PP13275,calphoglin,Epigenetics & Nuclear Signaling,Nuclear Receptor Signaling,Signal Transduction,Neuroscience,Calcium Signaling,CALCOCO1

Molekulargewicht: 67 kDa/70 kDa/77 kDa

Gen-ID: 57658

UniProt: Q9P1Z2

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Chromatin Binding