AUH Antikörper (AA 68-339)

Produktnummer ABIN6137369

Produktdetails anti-AUH Antikörper

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Bindungsspezifität: AA 68-339

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AUH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SSEMKTEDEL RVRHLEEENR GIVVLGINRA YGKNSLSKNL IKMLSKAVDA LKSDKKVRTI IIRSEVPGIF CAGADLKERA KMSSSEVGPF VSKIRAVIND IANLPVPTIA AIDGLALGGG LELALACDIR VAASSAKMGL VETKLAIIPG GGGTQRLPRA IGMSLAKELI FSARVLDGKE AKAVGLISHV LEQNQEGDAA YRKALDLARE FLPQGPVAMR VAKLAINQGM EVDLVTGLAI EEACYAQTIP TKDRLEGLLA FKEKRPPRYK GE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 68-339 of human AUH (NP_001689.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu AUH

Target: AUH (AU RNA Binding Protein/enoyl-CoA Hydratase (AUH))

Andere Bezeichnung: AUH (AUH Produkte)

Synonyme: C77140 antikoerper, W91705 antikoerper, wu:fb81b10 antikoerper, zgc:101057 antikoerper, AU RNA binding methylglutaconyl-CoA hydratase antikoerper, AU RNA binding protein/enoyl-coenzyme A hydratase antikoerper, AU RNA binding protein/enoyl-CoA hydratase antikoerper, AU RNA binding protein/enoyl-CoA hydratase S homeolog antikoerper, AUH antikoerper, Auh antikoerper, auh antikoerper, auh.S antikoerper

Hintergrund: This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants.,AUH,AUH

Molekulargewicht: 32 kDa/35 kDa

Gen-ID: 549

UniProt: Q13825