PHAP1 Antikörper (AA 1-170)

Produktnummer ABIN6136909

Produktdetails anti-PHAP1 Antikörper

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Bindungsspezifität: AA 1-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI NVGLTSIANL PKLNKLKKLE LSDNRVSGGL EVLAEKCPNL THLNLSGNKI KDLSTIEPLK KLENLKSLDL FNCEVTNLND YRENVFKLLP QLTYLDGYDR DDKEAPDSDA EGYVEGLDDE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PHAP1

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Andere Bezeichnung: ANP32A (ANP32A Produkte)

Synonyme: C15orf1 antikoerper, HPPCn antikoerper, I1PP2A antikoerper, LANP antikoerper, MAPM antikoerper, PHAP1 antikoerper, PHAPI antikoerper, PP32 antikoerper, Anp32 antikoerper, W91701 antikoerper, pp32 antikoerper, Anp32a antikoerper, CG5784 antikoerper, CT18148 antikoerper, CT42180 antikoerper, Dmel\\CG5784 antikoerper, anon-EST:fe3A2 antikoerper, wu:fj36e08 antikoerper, zgc:55516 antikoerper, ANP32D antikoerper, acidic nuclear phosphoprotein 32 family member A antikoerper, acidic (leucine-rich) nuclear phosphoprotein 32 family, member A antikoerper, CG5784 gene product from transcript CG5784-RB antikoerper, acidic nuclear phosphoprotein 32 family member A L homeolog antikoerper, ANP32A antikoerper, Anp32a antikoerper, Mapmodulin antikoerper, anp32a antikoerper, anp32a.L antikoerper

Hintergrund: Multifunctional protein that is involved in the regulation of many processes including tumor suppression, apoptosis, cell cycle progression or transcription. Promotes apoptosis by favouring the activation of caspase-9/CASP9 and allowing apoptosome formation. In addition, plays a role in the modulation of histone acetylation and transcription as part of the INHAT (inhibitor of histone acetyltransferases complex. Inhibits the histone-acetyltranferase activity of EP300/CREBBP (CREB-binding protein and EP300/CREBBP-associated factor by histone masking. Preferentially binds to unmodified histone H3 and sterically inhibiting its acetylation and phosphorylation leading to cell growth inhibition. Participates in other biochemical processes such as regulation of mRNA nuclear-to-cytoplasmic translocation and stability by its association with ELAVL1 (Hu-antigen R. Plays a role in E4F1-mediated transcriptional repression as well as inhibition of protein phosphatase 2A.,ANP32A,C15orf1,HPPCn,I1PP2A,LANP,MAPM,PHAP1,PHAPI,PP32,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,Caspases,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,ANP32A

Molekulargewicht: 28 kDa

Gen-ID: 8125

UniProt: P39687