IRS1 Antikörper (pSer307)

Produktnummer ABIN6225577

Produktdetails anti-IRS1 Antikörper

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Bindungsspezifität: pSer307

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TESIT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Phosphorylated Antibodies

Immunogen: A synthetic phosphorylated peptide around S307 of human IRS1 (NP_005535.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-IRS1 Antikörper (ABIN6225577)

Jia, Li, Feng, Shamoon, Sun, Ding, Zhang, Chen, Sun, Chen: "Anti-diabetic Effects of Clostridium butyricum CGMCC0313.1 through Promoting the Growth of Gut Butyrate-producing Bacteria in Type 2 Diabetic Mice." in: Scientific reports, Vol. 7, Issue 1, pp. 7046, (2017) (PubMed).

Details zu IRS1

Target: IRS1 (Insulin Receptor Substrate 1 (IRS1))

Andere Bezeichnung: IRS1 (IRS1 Produkte)

Synonyme: HIRS-1 antikoerper, G972R antikoerper, IRS-1 antikoerper, IRS1IRM antikoerper, irs1 antikoerper, irsu antikoerper, IRS1 antikoerper, irs-1 antikoerper, irs1-a antikoerper, insulin receptor substrate 1 antikoerper, insulin receptor substrate 2 antikoerper, insulin receptor substrate 1 S homeolog antikoerper, IRS1 antikoerper, Irs1 antikoerper, irs2 antikoerper, irs1.S antikoerper

Hintergrund: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.,HIRS-1,IRS1,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Diabetes,Obesity,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Protein phosphorylation,IRS1

Molekulargewicht: 131 kDa

Gen-ID: 3667

UniProt: P35568

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process