UGT1A6 Antikörper

Produktnummer ABIN5966012

Produktdetails anti-UGT1A6 Antikörper

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGT1A6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human UGT1A6 (NP_001063.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:1000 IHC 1:50-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu UGT1A6

Target: UGT1A6 (UDP Glucuronosyltransferase 1 Family, Polypeptide A6 (UGT1A6))

Andere Bezeichnung: UGT1A6 (UGT1A6 Produkte)

Synonyme: GNT1 antikoerper, HLUGP antikoerper, HLUGP1 antikoerper, UDPGT antikoerper, UDPGT 1-6 antikoerper, UGT1 antikoerper, UGT1A6S antikoerper, UGT1F antikoerper, UGT1A10 antikoerper, UGT1A6 antikoerper, UGT1A7 antikoerper, UGT1A8 antikoerper, UGT1A9 antikoerper, DKFZP469F071 antikoerper, UGT1A5 antikoerper, UGT antikoerper, Udpgt antikoerper, Ugt1 antikoerper, Ugt1a7 antikoerper, UGT1-06 antikoerper, UGT1.6 antikoerper, Ugt1a6b antikoerper, Ugt1a6 antikoerper, UDP glucuronosyltransferase family 1 member A6 antikoerper, UDP glucuronosyltransferase family 1 member A1 antikoerper, UDP glucuronosyltransferase 1 family, polypeptide A6 antikoerper, UDP-glucuronosyltransferase 1-1 antikoerper, UDP glucuronosyltransferase 1 family, polypeptide A6 S homeolog antikoerper, UDP-glucuronosyltransferase 1-6 antikoerper, UGT1A6 antikoerper, UGT1A1 antikoerper, LOC739942 antikoerper, ugt1a6.S antikoerper, ugt1a6 antikoerper, LOC100481084 antikoerper, Ugt1a6 antikoerper, UGT1-6 antikoerper, LOC100731122 antikoerper

Hintergrund: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants.

Molekulargewicht:

Observed_MW: 75kDa

Calculated_MW: 29kDa/50kDa/60kDa

Gen-ID: 54578

UniProt: P19224

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha