TUSC3 Antikörper

Produktnummer ABIN5961746

Produktdetails anti-TUSC3 Antikörper

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUSC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: D8S1992,MGC13453,N33,OST3A,Protein N33,Putative prostate cancer tumor suppressor,Tumor suppressor candidate 3,TUSC 3

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the Internal region of human N33

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TUSC3

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Andere Bezeichnung: N33 (TUSC3 Produkte)

Synonyme: zgc:110044 antikoerper, D8S1992 antikoerper, M33 antikoerper, MRT22 antikoerper, MRT7 antikoerper, N33 antikoerper, OST3A antikoerper, AU022242 antikoerper, BC003311 antikoerper, tumor suppressor candidate 3 antikoerper, tumor suppressor candidate 3 L homeolog antikoerper, TUSC3 antikoerper, tusc3 antikoerper, tusc3.L antikoerper, CpipJ_CPIJ005611 antikoerper, Tusc3 antikoerper

Hintergrund: This gene is a candidate tumor suppressor gene. It is located within a homozygously deleted region of a metastatic prostate cancer. The gene is expressed in most nonlymphoid human tissues including prostate, lung, liver, and colon. Expression was also detected in many epithelial tumor cell lines. Two transcript variants encoding distinct isoforms have been identified for this gene.TUSC3 (Tumor Suppressor Candidate 3) is a Protein Coding gene. Diseases associated with TUSC3 include Autosomal Recessive Non-Syndromic Intellectual Disability and Non-Syndromic Intellectual Disability. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Protein processing in endoplasmic reticulum. GO annotations related to this gene include magnesium ion transmembrane transporter activity and dolichyl-diphosphooligosaccharide-protein glycotransferase activity. An important paralog of this gene is MAGT1.

Molekulargewicht: 40kDa

Gen-ID: 7991

UniProt: Q13454

Pathways: Cell RedoxHomeostasis