MID1 Antikörper

Produktnummer ABIN5958299

Produktdetails anti-MID1 Antikörper

Target: MID1 (Midline 1 (MID1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MID1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: BBBG 1,BBBG1,E3 ubiquitin-protein ligase Midline-1,Finger on X and Y mouse homolog of,FXY,GBBB 1,GBBB1,MID 1,Mid1,Midin,Midline 1 (Opitz/BBB syndrome),Midline 1,Midline 1 ring finger,Midline 1 RING finger protein,Midline-1,Midline1,OGS 1,OGS1,OS,OSX,Putative transcription factor XPRF,RING finger protein 59,RING finger protein Midline-1,RNF 59,RNF59,TRI18,TRI18,TRIM 18,TRIM18,Tripartite motif containing protein 18,Tripartite motif protein TRIM18,Tripartite motif-containing protein 18,XPRF,zinc finger on X and Y,mouse,homolog of,Zinc finger X and Y,ZNFXY

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the N-terminal region of human Midline-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MID1

Target: MID1 (Midline 1 (MID1))

Andere Bezeichnung: Midline-1 (MID1 Produkte)

Synonyme: BBBG1 antikoerper, FXY antikoerper, GBBB1 antikoerper, MIDIN antikoerper, OGS1 antikoerper, OS antikoerper, OSX antikoerper, RNF59 antikoerper, TRIM18 antikoerper, XPRF antikoerper, ZNFXY antikoerper, 61B3-R antikoerper, DXHXS1141 antikoerper, Fxy antikoerper, Trim18 antikoerper, Midline1 antikoerper, bbbg1 antikoerper, fxy antikoerper, gbbb1 antikoerper, midin antikoerper, ogs1 antikoerper, osx antikoerper, rnf59 antikoerper, trim18 antikoerper, xprf antikoerper, znfxy antikoerper, midline 1 antikoerper, midline 1 L homeolog antikoerper, MID1 antikoerper, Mid1 antikoerper, mid1 antikoerper, mid1.L antikoerper

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family, also known as the 'RING-B box-coiled coil' (RBCC) subgroup of RING finger proteins. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein forms homodimers which associate with microtubules in the cytoplasm. The protein is likely involved in the formation of multiprotein structures acting as anchor points to microtubules. Mutations in this gene have been associated with the X-linked form of Opitz syndrome, which is characterized by midline abnormalities such as cleft lip, laryngeal cleft, heart defects, hypospadias, and agenesis of the corpus callosum. This gene was also the first example of a gene subject to X inactivation in human while escaping it in mouse. Alternative promoter use, alternative splicing and alternative polyadenylation result in multiple transcript variants that have different tissue specificities.

Molekulargewicht: 75kDa

Gen-ID: 4281

UniProt: O15344