A synthetic peptide from the c-terminal region of human KCNN4 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Reconstitute in 500 μL of MQ water. Centrifuge to remove any insoluble material.
Handhabung
Avoid freeze and thaw cycles.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit
12 months
Target
KCNN4
(Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 4 (KCNN4))
Function: Forms a voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization which promotes calcium influx. The channel is blocked by clotrimazole and charybdotoxin but is insensitive to apamin. Subcellular location: Membrane, Multi-pass membrane protein. Tissue specificity: Widely expressed in non-excitable tissues.,Calcium-activated,Intermediate conductance calcium-activated potassium channel protein 4, SK4, KCa4, IKCa1, IK1, IK1, IKCA1, KCA4, SK4