CDC45 Antikörper

Produktnummer ABIN5708443

Produktdetails anti-CDC45 Antikörper

Target: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC45 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): Expected species reactivity: Human

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids E166-A431 was used as the immunogen for the CDC45 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CDC45 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL, Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CDC45 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CDC45

Target: CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

Andere Bezeichnung: CDC45 / PORC-PI-1 (CDC45 Produkte)

Synonyme: cdc45l antikoerper, cdc45l2 antikoerper, porc-pi-1 antikoerper, CDC45L antikoerper, CDC45L2 antikoerper, PORC-PI-1 antikoerper, Cdc45l antikoerper, cell division cycle 45 antikoerper, cell division cycle 45 S homeolog antikoerper, cell division cycle 45 L homeolog antikoerper, cdc45 antikoerper, CDC45 antikoerper, cdc45.S antikoerper, Cdc45 antikoerper, cdc45.L antikoerper

Hintergrund: Cell division control protein 45 homolog was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

UniProt: O75419

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA