RTEL1 Antikörper

Produktnummer ABIN5708351

Produktdetails anti-RTEL1 Antikörper

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTEL1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Kreuzreaktivität (Details): Expected species reactivity: Human

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human protein corresponding to amino acids R651-M756 was used as the immunogen for the RTEL1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RTEL1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the RTEL1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Andere Bezeichnung: RTEL1 (RTEL1 Produkte)

Synonyme: F18B13.3 antikoerper, F18B13_3 antikoerper, C20orf41 antikoerper, DKCB5 antikoerper, NHL antikoerper, RTEL antikoerper, bK3184A7.3 antikoerper, AI451565 antikoerper, AW540478 antikoerper, Rtel antikoerper, RGD1306721 antikoerper, zgc:113114 antikoerper, regulator of telomere elongation helicase 1 antikoerper, RAD3-like DNA-binding helicase protein antikoerper, RTEL1 antikoerper, rtel1 antikoerper, AT1G79950 antikoerper, LOC100286037 antikoerper, Rtel1 antikoerper

Hintergrund: The RTEL1 gene encodes a DNA helicase which functions in the stability, protection and elongation of telomeres and interacts with proteins in the shelterin complex known to protect telomeres during DNA replication. Mutations in this gene have been associated with dyskeratosis congenita and Hoyerall-Hreidarsson syndrome. Read-through transcription of this gene into the neighboring downstream gene, which encodes tumor necrosis factor receptor superfamily, member 6b, generates a non-coding transcript. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q9NZ71