MX1 Antikörper

Produktnummer ABIN5705684

Produktdetails anti-MX1 Antikörper

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Immunogen: myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 ( Mouse )

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse spleen tissue were subjected to SDS PAGE followed by western blot with FNab05450(MX1 antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Andere Bezeichnung: MX1 (MX1 Produkte)

Synonyme: IFI78 antikoerper, AI893580 antikoerper, Mx antikoerper, Mx-1 antikoerper, IFI-78K antikoerper, MX antikoerper, MxA antikoerper, Mx1-b antikoerper, Mx1B antikoerper, OGTPBP antikoerper, ONBP antikoerper, myxovirus (influenza virus) resistance 1 antikoerper, MX dynamin-like GTPase 1 antikoerper, MX dynamin like GTPase 1 antikoerper, Mx1 antikoerper, MX1 antikoerper

Hintergrund: Synonyms:IFI 78K, IFI78, Interferon induced protein p78, MX, MX1, MxA, Myxovirus resistance protein 1 Background:Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Molekulargewicht: 76 kDa

Gen-ID: 4599

UniProt: P20591