TELO2 Antikörper

Produktnummer ABIN5705560

Produktdetails anti-TELO2 Antikörper

Target: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TELO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogen: TEL2, telomere maintenance 2, homolog (S. cerevisiae)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

A431 cells were subjected to SDS PAGE followed by western blot with FNab08592(TELO2 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TELO2

Target: TELO2 (TEL2, Telomere Maintenance 2, Homolog (TELO2))

Andere Bezeichnung: TELO2 (TELO2 Produkte)

Synonyme: RGD1305553 antikoerper, 1200003M09Rik antikoerper, AI415602 antikoerper, Tel2 antikoerper, mKIAA0683 antikoerper, CLK2 antikoerper, TEL2 antikoerper, telomere maintenance 2 antikoerper, Telo2 antikoerper, TELO2 antikoerper

Hintergrund: Synonyms:KIAA0683 Background:Regulator of the DNA damage response(DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase(PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation(IR), ultraviolet(UV) and mitomycin C(MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals. May be involved in telomere length regulation.

Gen-ID: 9894

UniProt: Q9Y4R8