WRAP53 Antikörper
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- Target Alle WRAP53 Antikörper anzeigen
- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
- Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser WRAP53 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
- Immunogen
- WD repeat containing, antisense to TP53
- Isotyp
- IgG
- Top Product
- Discover our top product WRAP53 Primärantikörper
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- Applikationshinweise
- WB:1:500-1:5000,IHC:1:20-1:200,IP:1:200-1:1000
- Kommentare
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human kidney tissue were subjected to SDS PAGE followed by western blot with FNab09523(WRAP53 antibody) at dilution of 1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
- Andere Bezeichnung
- WRAP53 (WRAP53 Produkte)
- Synonyme
- DKCB3 antikoerper, TCAB1 antikoerper, WDR79 antikoerper, Wdr79 antikoerper, BC021790 antikoerper, WD repeat containing antisense to TP53 antikoerper, WD repeat containing, antisense to TP53 antikoerper, WD repeat containing, antisense to Trp53 antikoerper, WRAP53 antikoerper, Wrap53 antikoerper
- Hintergrund
- Synonyms:FLJ10385, TCAB1, WDR79, WRAP53 Background:Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
- Molekulargewicht
- 39kDa
- Gen-ID
- 55135
- UniProt
- Q9BUR4
- Pathways
- Telomere Maintenance
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