RSPO2 Antikörper

Produktnummer ABIN5705242

Produktdetails anti-RSPO2 Antikörper

Target: RSPO2 (R-Spondin 2 (RSPO2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RSPO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: R-spondin 2 homolog (Xenopus laevis)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu RSPO2

Target: RSPO2 (R-Spondin 2 (RSPO2))

Andere Bezeichnung: RSPO2 (RSPO2 Produkte)

Synonyme: RGD1562331 antikoerper, CRISTIN2 antikoerper, 2610028F08Rik antikoerper, AA673245 antikoerper, D430027K22 antikoerper, ftls antikoerper, R-spondin 2 antikoerper, R-spondin 2 L homeolog antikoerper, Rspo2 antikoerper, rspo2.L antikoerper, rspo2 antikoerper, RSPO2 antikoerper

Hintergrund: Synonyms:CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2 Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

Gen-ID: 340419

UniProt: Q6UXX9