UNC13A/Munc13-1 Antikörper

Produktnummer ABIN5704978

Produktdetails anti-UNC13A/Munc13-1 Antikörper

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UNC13A/Munc13-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: unc-13 homolog A (C. elegans)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000,IP:1:200-1:2000

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab09255(UNC13A antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu UNC13A/Munc13-1

Target: UNC13A/Munc13-1 (UNC13A) (Unc-13 Homolog A (UNC13A))

Andere Bezeichnung: UNC13A/Munc13-1 (UNC13A Produkte)

Synonyme: Munc13-1 antikoerper, Unc13h1 antikoerper, 2410078G03Rik antikoerper, unc-13 homolog A antikoerper, unc-13 homolog A (C. elegans) antikoerper, Unc13a antikoerper, UNC13A antikoerper

Hintergrund: Synonyms:KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A(C. elegans), UNC13A Background:UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool(RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion. The antibody is specific to UNC13A.

Molekulargewicht: 27kDa

Pathways: Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis