THOC6 Antikörper

Produktnummer ABIN5704556

Produktdetails anti-THOC6 Antikörper

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser THOC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: THO complex 6 homolog (Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

A431 cells were subjected to SDS PAGE followed by western blot with FNab08669(THOC6 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu THOC6

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Andere Bezeichnung: THOC6 (THOC6 Produkte)

Synonyme: WDR58 antikoerper, fSAP35 antikoerper, F830014G06Rik antikoerper, Wdr58 antikoerper, Pdrp antikoerper, zgc:101618 antikoerper, thoc6 antikoerper, THO complex 6 antikoerper, THO complex 6 homolog (Drosophila) antikoerper, THO complex 6 L homeolog antikoerper, THOC6 antikoerper, Thoc6 antikoerper, thoc6 antikoerper, thoc6.L antikoerper

Hintergrund: Synonyms:WDR58 Background:Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

Gen-ID: 79228

UniProt: Q86W42