VAMP8 Antikörper

Produktnummer ABIN5704541

Produktdetails anti-VAMP8 Antikörper

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VAMP8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: vesicle-associated membrane protein 8 (endobrevin)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:1000

Kommentare:

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab09365( VAMP8 Antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu VAMP8

Target: VAMP8 (Vesicle-Associated Membrane Protein 8 (Endobrevin) (VAMP8))

Andere Bezeichnung: VAMP8 (VAMP8 Produkte)

Synonyme: vamp8 antikoerper, EDB antikoerper, VAMP-8 antikoerper, AU041171 antikoerper, Edb antikoerper, endobrevin antikoerper, wu:fa18d07 antikoerper, zgc:56588 antikoerper, vesicle associated membrane protein 8 antikoerper, vesicle-associated membrane protein 8 (endobrevin) antikoerper, vesicle-associated membrane protein 8 antikoerper, vamp8 antikoerper, VAMP8 antikoerper, Vamp8 antikoerper

Hintergrund: Synonyms:EDB, Endobrevin, VAMP 8, VAMP8 Background:SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane via its interaction with the STX17-SNAP29 binary t-SNARE complex(PubMed:23217709, PubMed:25686604). Also required for dense-granule secretion in platelets(PubMed:12130530). Plays also a role in regulated enzyme secretion in pancreatic acinar cells(By similarity). Involved in the abscission of the midbody during cell division, which leads to completely separate daughter cells(By similarity). Involved in the homotypic fusion of early and late endosomes(By similarity).

Molekulargewicht: 20kDa,observed 20kDa,50kDa

Gen-ID: 8673

UniProt: Q9BV40