USP5 Antikörper
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- Target Alle USP5 Antikörper anzeigen
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser USP5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Immunogen
- ubiquitin specific peptidase 5 (isopeptidase T)
- Isotyp
- IgG1
- Top Product
- Discover our top product USP5 Primärantikörper
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- Applikationshinweise
- WB : 1:500-1:5000
- Kommentare
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab09341( USP5 Antibody) at dilution of 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- USP5 (Ubiquitin Specific Peptidase 5 (USP5))
- Andere Bezeichnung
- USP5 (USP5 Produkte)
- Synonyme
- ISOT antikoerper, AA407472 antikoerper, ISOT-1 antikoerper, Ucht antikoerper, ubiquitin specific peptidase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5 antikoerper, ubiquitin carboxyl-terminal hydrolase 5, putative antikoerper, ubiquitin specific protease 5 antikoerper, ubiquitin specific peptidase 5 (isopeptidase T) antikoerper, USP5 antikoerper, CNH02890 antikoerper, EHI_049940 antikoerper, CC1G_12961 antikoerper, MCYG_01862 antikoerper, CGB_L3600C antikoerper, PY00546 antikoerper, Usp5 antikoerper
- Hintergrund
- Synonyms:Deubiquitinating enzyme 5, Isopeptidase T, ISOT, Ubiquitin thiolesterase 5, USP5 Background:Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys-63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.
- Molekulargewicht
- 93kDa
- Gen-ID
- 8078
- UniProt
- P45974
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