TRIM33 Antikörper

Produktnummer ABIN5704459

Produktdetails anti-TRIM33 Antikörper

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: tripartite motif-containing 33

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:200-1:2000

Kommentare:

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08981(TRIM33 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TRIM33

Target: TRIM33 (Tripartite Motif Containing 33 (TRIM33))

Andere Bezeichnung: TRIM33 (TRIM33 Produkte)

Synonyme: TRIM33 antikoerper, ptc7 antikoerper, rfg7 antikoerper, tf1g antikoerper, tif1g antikoerper, tifgamma antikoerper, MGC146665 antikoerper, tif1gamma antikoerper, ECTO antikoerper, PTC7 antikoerper, RFG7 antikoerper, TF1G antikoerper, TIF1G antikoerper, TIF1GAMMA antikoerper, TIFGAMMA antikoerper, ecto antikoerper, 8030451N04Rik antikoerper, AI413936 antikoerper, Ecto antikoerper, Tif1g antikoerper, ectodermin antikoerper, mKIAA1113 antikoerper, cb1085 antikoerper, id:ibd2175 antikoerper, mon antikoerper, wu:fc17f10 antikoerper, zgc:136680 antikoerper, tripartite motif containing 33 antikoerper, tripartite motif containing 33 L homeolog antikoerper, tripartite motif-containing 33 antikoerper, TRIM33 antikoerper, trim33 antikoerper, trim33.L antikoerper, Trim33 antikoerper

Hintergrund: Synonyms:Ectodermin homolog, FLJ32925, KIAA1113, Protein Rfg7, PTC7, RET fused gene 7 protein, RFG7, TF1G, TIF1 gamma, TIF1G, TIF1GAMMA, TIFGAMMA, TRIM33, tripartite motif containing 33 Background:Acts as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor(By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade(Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).

Molekulargewicht: 72kDa

Gen-ID: 51592

UniProt: Q9UPN9