GPSM1 Antikörper

Produktnummer ABIN5703533

Produktdetails anti-GPSM1 Antikörper

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPSM1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: G-protein signaling modulator 1 (AGS3-like, C. elegans)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:2000,IF:1:10-1:100,IHC:1:20-1:200

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00221(GPSM1 antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GPSM1

Target: GPSM1 (G-Protein Signaling Modulator 1 (GPSM1))

Andere Bezeichnung: AGS3 (GPSM1 Produkte)

Synonyme: 1810037C22Rik antikoerper, AW107933 antikoerper, Ags3 antikoerper, AGS3 antikoerper, ags3 antikoerper, gpsm1 antikoerper, G-protein signalling modulator 1 (AGS3-like, C. elegans) antikoerper, G-protein signaling modulator 1 antikoerper, G protein signaling modulator 1 antikoerper, G-protein signaling modulator 1 L homeolog antikoerper, Gpsm1 antikoerper, GPSM1 antikoerper, gpsm1.L antikoerper

Hintergrund: Synonyms:AGS3, DKFZp727I051, GPSM1 Background:GPSM1, also named as AGS3, is a receptor-independent G protein activator that has been implicated in multiple biological events such as brain development, neuroplasticity and addiction, cardiac function, Golgi structure/function, macroautophagy and metabolism. It contains seven tetratricopeptide repeats in its N-terminal half and four G-protein regulatory(GPR) motifs in its C-terminal half. It has been shown that AGS3 could regulate the orientation of the mitotic spindle, cAMP production, membrane protein transport, and asymmetric cell division by binding preferentially to inactive Gai/o subunits complexed with guanine dinucleotide phosphate(GDP) at multiple G-protein regulatory or GoLoco motif repeats. It also plays an important anti-apoptotic role through enhancing the phosphorylation of cyclic AMP response element-binding protein(p-CREB).

Molekulargewicht: 72kDa

UniProt: Q86YR5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling