PABPC4 Antikörper

Produktnummer ABIN5703338

Produktdetails anti-PABPC4 Antikörper

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PABPC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Immunogen: poly(A) binding protein, cytoplasmic 4 (inducible form)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse heart tissue were subjected to SDS PAGE followed by western blot with FNab06098(PABPC4 antibody) at dilution of 1:400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu PABPC4

Target: PABPC4 (Poly(A) Binding Protein, Cytoplasmic 4 (Inducible Form) (PABPC4))

Andere Bezeichnung: PABPC4 (PABPC4 Produkte)

Synonyme: cb12 antikoerper, sb:cb12 antikoerper, PABP antikoerper, ePAB antikoerper, ePABP antikoerper, APP-1 antikoerper, APP1 antikoerper, PABP4 antikoerper, iPABP antikoerper, polyadenylate-binding protein 4 antikoerper, poly(A) binding protein, cytoplasmic 4 antikoerper, poly(A) binding protein, cytoplasmic 4 (inducible form) antikoerper, poly(A) binding protein cytoplasmic 4 L homeolog antikoerper, poly(A) binding protein cytoplasmic 4 antikoerper, Bm1_06880 antikoerper, Pabpc4 antikoerper, pabpc4 antikoerper, pabpc4.L antikoerper, PABPC4 antikoerper

Hintergrund: Synonyms:APP1, PABP4 Background:Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gen-ID: 8761

UniProt: Q13310

Pathways: SARS-CoV-2 Protein Interaktom