F2RL1 Antikörper

Produktnummer ABIN5703335

Produktdetails anti-F2RL1 Antikörper

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F2RL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: coagulation factor II (thrombin) receptor-like 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000

Kommentare:

COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab06145( F2RL1 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu F2RL1

Target: F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))

Andere Bezeichnung: PAR2 (F2RL1 Produkte)

Synonyme: par2 antikoerper, GPR11 antikoerper, PAR2 antikoerper, Gpcr11 antikoerper, PAR-2 antikoerper, Par2 antikoerper, Par-2 antikoerper, Proteinase-activated receptor 2 antikoerper, F2R like trypsin receptor 1 antikoerper, coagulation factor II (thrombin) receptor-like 1 antikoerper, par2 antikoerper, F2RL1 antikoerper, F2rl1 antikoerper

Hintergrund: Synonyms:F2RL1, G protein coupled receptor 11, GPR11, PAR 2, PAR2, Thrombin receptor like 1 Background:Proteinase-activated receptors(PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells(e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions, respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction, and cancers.(PMID:23895492)

Molekulargewicht: 50kDa

UniProt: P55085

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom