LRWD1 Antikörper

Produktnummer ABIN5703091

Produktdetails anti-LRWD1 Antikörper

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRWD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: leucine-rich repeats and WD repeat domain containing 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu LRWD1

Target: LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))

Andere Bezeichnung: LRWD1 (LRWD1 Produkte)

Synonyme: CENP-33 antikoerper, ORCA antikoerper, 1200011O22Rik antikoerper, AU042569 antikoerper, AW548074 antikoerper, Orca antikoerper, si:dkey-261j4.9 antikoerper, wu:fb78b03 antikoerper, wu:ft31b04 antikoerper, leucine rich repeats and WD repeat domain containing 1 antikoerper, leucine-rich repeats and WD repeat domain containing 1 antikoerper, microRNA 5090 antikoerper, leucine-rich repeats and WD repeat domain containing 1 L homeolog antikoerper, LRWD1 antikoerper, Lrwd1 antikoerper, lrwd1 antikoerper, MIR5090 antikoerper, lrwd1.L antikoerper

Hintergrund: Synonyms:CENP-33, ORCA Background:Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.

Molekulargewicht: 85 kDa

Gen-ID: 222229

UniProt: Q9UFC0

Pathways: Chromatin Binding