LONP1 Antikörper

Produktnummer ABIN5702491

Produktdetails anti-LONP1 Antikörper

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LONP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: lon peptidase 1, mitochondrial

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab04821( LONP1 Antibody) at dilution of 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1 (LONP1 Produkte)

Synonyme: PRSS15 antikoerper, prss15 antikoerper, fc64d11 antikoerper, wu:fc64d11 antikoerper, LON antikoerper, LONP antikoerper, LonHS antikoerper, PIM1 antikoerper, hLON antikoerper, 1200017E13Rik antikoerper, Prss15 antikoerper, Lon antikoerper, lon peptidase 1, mitochondrial antikoerper, ATP-dependent Lon protease antikoerper, LONP1 antikoerper, lonp1 antikoerper, Lonp1 antikoerper, PIM1 antikoerper

Hintergrund: Synonyms:PRSS15 Background:ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory(StAR) protein.

Molekulargewicht: 100 kDa

Gen-ID: 9361

UniProt: P36776