BMPR2 Antikörper

Produktnummer ABIN5702180

Produktdetails anti-BMPR2 Antikörper

Target: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: bone morphogenetic protein receptor, type II (serine/threonine kinase)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu BMPR2

Target: BMPR2 (Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Andere Bezeichnung: BMPR2 (BMPR2 Produkte)

Synonyme: BMPR-II antikoerper, BMPR3 antikoerper, BMR2 antikoerper, BRK-3 antikoerper, PPH1 antikoerper, T-ALK antikoerper, 2610024H22Rik antikoerper, AL117858 antikoerper, AW546137 antikoerper, BB189135 antikoerper, BMP-2 antikoerper, BMPR-2 antikoerper, BMPRII antikoerper, Gm20272 antikoerper, Bmpr-II antikoerper, bmprii antikoerper, bone morphogenetic protein receptor type 2 antikoerper, bone morphogenetic protein receptor, type II b (serine/threonine kinase) antikoerper, bone morphogenetic protein receptor, type II (serine/threonine kinase) antikoerper, BMPR2 antikoerper, bmpr2b antikoerper, Bmpr2 antikoerper

Hintergrund: Synonyms:PPH1 Background:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Molekulargewicht: 120 kDa,97 kDa

Gen-ID: 659

UniProt: Q13873

Pathways: Growth Factor Binding