LARGE Antikörper

Produktnummer ABIN5701848

Produktdetails anti-LARGE Antikörper

Target: LARGE (Like-Glycosyltransferase (LARGE))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LARGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: like-glycosyltransferase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu LARGE

Target: LARGE (Like-Glycosyltransferase (LARGE))

Andere Bezeichnung: LARGE (LARGE Produkte)

Synonyme: gyltl1b antikoerper, gyltl1b-b antikoerper, mdc1d antikoerper, MDC1D antikoerper, MDDGA6 antikoerper, MDDGB6 antikoerper, BPFD36 antikoerper, Gyltl1a antikoerper, Mbp-1 antikoerper, Mbp1 antikoerper, enr antikoerper, fg antikoerper, froggy antikoerper, mKIAA0609 antikoerper, myd antikoerper, NV15834 antikoerper, DKFZp459G0120 antikoerper, LARGE xylosyl- and glucuronyltransferase 1 L homeolog antikoerper, LARGE xylosyl- and glucuronyltransferase 1 antikoerper, glycosyltransferase-like protein LARGE1 antikoerper, like-glycosyltransferase antikoerper, large1.L antikoerper, LARGE1 antikoerper, Large1 antikoerper, large1 antikoerper, LOC100118066 antikoerper, LARGE antikoerper, Large antikoerper

Hintergrund: Synonyms:KIAA0609, LARGE1 Background:Bifunctional glycosyltransferase with both xylosyltransferase and beta-1,3-glucuronyltransferase activities involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide(N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan(DAG1)(PubMed:22223806). Phosphorylated O-mannosyl trisaccharid is required for binding laminin G-like domain-containing extracellular proteins with high affinity and plays a key role in skeletal muscle function and regeneration. LARGE elongates the glucuronyl-beta-1,4-xylose-beta disaccharide primer structure initiated by B3GNT1/B4GAT1 by adding repeating units [-3-Xylose-alpha-1,3-GlcA-beta-1-] to produce a heteropolysaccharide(PubMed:25279699).

Molekulargewicht: 65-70 kDa

Gen-ID: 9215

UniProt: O95461