ABHD2 Antikörper

Produktnummer ABIN5701505

Produktdetails anti-ABHD2 Antikörper

Target: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABHD2 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogen: abhydrolase domain containing 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:500-1:5000,IHC:1:20-1:200

Kommentare:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00049(ABHD2 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ABHD2

Target: ABHD2 (Abhydrolase Domain Containing 2 (ABHD2))

Andere Bezeichnung: ABHD2 (ABHD2 Produkte)

Synonyme: HS1-2 antikoerper, LABH2 antikoerper, PHPS1-2 antikoerper, abhd2 antikoerper, zgc:55722 antikoerper, 2210009N18Rik antikoerper, Labh-2 antikoerper, zgc:153750 antikoerper, abhydrolase domain containing 2 antikoerper, abhydrolase domain containing 2a antikoerper, abhydrolase domain containing 2b antikoerper, ABHD2 antikoerper, Abhd2 antikoerper, abhd2a antikoerper, abhd2 antikoerper, abhd2b antikoerper

Hintergrund: Synonyms:ABHD2, Protein PHPS1 2, HS1 2, Lung alpha/beta hydrolase 2, LABH2 Background:Progesterone-dependent acylglycerol lipase that catalyzes hydrolysis of endocannabinoid arachidonoylglycerol(AG) from cell membrane(PubMed:26989199). Acts as a progesterone receptor: progesterone-binding activates the acylglycerol lipase activity, mediating degradation of 1-arachidonoylglycerol(1AG) and 2-arachidonoylglycerol(2AG) to glycerol and arachidonic acid(AA)(PubMed:26989199). Plays a key role in sperm capacitation in response to progesterone by mediating degradation of 2AG, an inhibitor of the sperm calcium channel CatSper, leading to calcium influx via CatSper and sperm activation(PubMed:26989199). May also play a role in smooth muscle cells migration(By similarity).

Molekulargewicht: 48kDa

Gen-ID: 11057

UniProt: P08910