Urm1 Antikörper

Produktnummer ABIN5701377

Produktdetails anti-Urm1 Antikörper

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Urm1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: ubiquitin related modifier 1 homolog (S. cerevisiae)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000,IHC:1:20-1:200

Kommentare:

human placenta tissue were subjected to SDS PAGE followed by western blot with FNab09289(URM1 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu Urm1

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Andere Bezeichnung: URM1 (Urm1 Produkte)

Synonyme: RGD1306599 antikoerper, C9orf74 antikoerper, 2900073H19Rik antikoerper, ubiquitin related modifier 1 antikoerper, ubiquitin related modifier antikoerper, ubiquitin-related modifier antikoerper, Ubiquitin-related modifier 1 homolog antikoerper, Urm1 antikoerper, LOC733109 antikoerper, URM1 antikoerper

Hintergrund: Synonyms:URM1, C9orf74 Background:Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated(-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein(UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.

Molekulargewicht: 104kDa

Gen-ID: 81605

UniProt: Q9BTM9