GRB14 Antikörper

Produktnummer ABIN5700940

Produktdetails anti-GRB14 Antikörper

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRB14 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogen: growth factor receptor-bound protein 14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

DU 145 cells were subjected to SDS PAGE followed by western blot with FNab03641( GRB14 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu GRB14

Target: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Andere Bezeichnung: GRB14 (GRB14 Produkte)

Synonyme: GRB14 antikoerper, AI505286 antikoerper, growth factor receptor bound protein 14 antikoerper, GRB14 antikoerper, grb14 antikoerper, Grb14 antikoerper

Hintergrund: Synonyms: Background:Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor(INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Molekulargewicht: 61 kDa

Gen-ID: 2888

UniProt: Q14449