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DACH1 Antikörper

DACH1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5700688
  • Target Alle DACH1 Antikörper anzeigen
    DACH1 (Dachshund 1 (DACH1))
    Reaktivität
    • 51
    • 17
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 51
    • 1
    Kaninchen
    Klonalität
    • 52
    Polyklonal
    Konjugat
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DACH1 Antikörper ist unkonjugiert
    Applikation
    • 44
    • 23
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Immunogen
    dachshund homolog 1 (Drosophila)
    Isotyp
    IgG
    Top Product
    Discover our top product DACH1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02230( DACH1 Antibody) at dilution of 1:600

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    DACH1 (Dachshund 1 (DACH1))
    Andere Bezeichnung
    DACH1 (DACH1 Produkte)
    Synonyme
    DACH antikoerper, AI182278 antikoerper, Dac antikoerper, Dach antikoerper, E130112M23Rik antikoerper, dach antikoerper, dachshund family transcription factor 1 antikoerper, dachshund 1 (Drosophila) antikoerper, dachshund family transcription factor 1 S homeolog antikoerper, dachshund homolog 1 antikoerper, DACH1 antikoerper, Dach1 antikoerper, dach1.S antikoerper, dach1 antikoerper, LOC100550020 antikoerper
    Hintergrund
    Synonyms:DACH Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter(By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain(By similarity).
    Molekulargewicht
    97-100 kDa
    Gen-ID
    1602
    UniProt
    Q9UI36
    Pathways
    Feeding Behaviour
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