DACH1 Antikörper
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- Target Alle DACH1 Antikörper anzeigen
- DACH1 (Dachshund 1 (DACH1))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DACH1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Immunogen
- dachshund homolog 1 (Drosophila)
- Isotyp
- IgG
- Top Product
- Discover our top product DACH1 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab02230( DACH1 Antibody) at dilution of 1:600
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- DACH1 (Dachshund 1 (DACH1))
- Andere Bezeichnung
- DACH1 (DACH1 Produkte)
- Synonyme
- DACH antikoerper, AI182278 antikoerper, Dac antikoerper, Dach antikoerper, E130112M23Rik antikoerper, dach antikoerper, dachshund family transcription factor 1 antikoerper, dachshund 1 (Drosophila) antikoerper, dachshund family transcription factor 1 S homeolog antikoerper, dachshund homolog 1 antikoerper, DACH1 antikoerper, Dach1 antikoerper, dach1.S antikoerper, dach1 antikoerper, LOC100550020 antikoerper
- Hintergrund
- Synonyms:DACH Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter(By similarity). Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain(By similarity).
- Molekulargewicht
- 97-100 kDa
- Gen-ID
- 1602
- UniProt
- Q9UI36
- Pathways
- Feeding Behaviour
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