CC2D1A Antikörper

Produktnummer ABIN5700435

Produktdetails anti-CC2D1A Antikörper

Target: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CC2D1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Immunogen: coiled-coil and C2 domain containing 1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab01335(CC2D1A antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CC2D1A

Target: CC2D1A (Coiled-Coil and C2 Domain Containing 1A (CC2D1A))

Andere Bezeichnung: CC2D1A (CC2D1A Produkte)

Synonyme: mrt3 antikoerper, freud-1 antikoerper, FREUD-1 antikoerper, Freud-1/Aki1 antikoerper, MRT3 antikoerper, BC016188 antikoerper, Freud-1 antikoerper, Tape antikoerper, RGD1306108 antikoerper, coiled-coil and C2 domain containing 1A antikoerper, CC2D1A antikoerper, cc2d1a antikoerper, Cc2d1a antikoerper

Hintergrund: Synonyms:AKI1 Background:Transcription factor that binds specifically to the DRE(dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses(By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regulates spindle pole localization of the cohesin subunit SCC1/RAD21, thereby mediating centriole cohesion during mitosis.

Molekulargewicht: 130 kDa, 104 kDa

Gen-ID: 54862

UniProt: Q6P1N0