CACNA1S Antikörper

Produktnummer ABIN5700411

Produktdetails anti-CACNA1S Antikörper

Target: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1S Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: calcium channel, voltage-dependent, L type, alpha 1S subunit

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab01173(CACNA1S antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CACNA1S

Target: CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))

Andere Bezeichnung: CACNA1S (CACNA1S Produkte)

Synonyme: CACNA1S antikoerper, cav1.1 antikoerper, ca(v)1.1 antikoerper, CACNL1A3 antikoerper, CCHL1A3 antikoerper, Cav1.1 antikoerper, HOKPP antikoerper, HOKPP1 antikoerper, MHS5 antikoerper, TTPP1 antikoerper, hypoPP antikoerper, AW493108 antikoerper, Cchl1a3 antikoerper, fmd antikoerper, mdg antikoerper, sj antikoerper, caV1.1 antikoerper, calcium voltage-gated channel subunit alpha1 S antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antikoerper, calcium channel, voltage-dependent, L type, alpha 1S subunit antikoerper, CACNA1S antikoerper, cacna1s.S antikoerper, Cacna1s antikoerper

Hintergrund: Synonyms:CACH1, CACN1, CACNL1A3 Background:Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting(L-type) calcium channels belong to the 'high-voltage activated'(HVA) group. They are blocked by dihydropyridines(DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA(omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA(omega-CTx-GVIA) and omega-agatoxin-IVA(omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

Molekulargewicht: 200-220 kDa

Gen-ID: 779

UniProt: Q13698

Pathways: Skeletal Muscle Fiber Development