ANGPTL4 Antikörper

Produktnummer ABIN5700248

Produktdetails anti-ANGPTL4 Antikörper

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Immunogen: angiopoietin-like 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:2000,IHC:1:20-1:200,IF:1:20-1:200,IP:1:200-1:2000

Kommentare:

HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab00399( ANGPTL4 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4 (ANGPTL4 Produkte)

Synonyme: ANGPTL2 antikoerper, ARP4 antikoerper, FIAF antikoerper, HFARP antikoerper, NL2 antikoerper, PGAR antikoerper, pp1158 antikoerper, Arp4 antikoerper, Bk89 antikoerper, Fiaf antikoerper, Hfarp antikoerper, Ng27 antikoerper, Pgar antikoerper, Pgarg antikoerper, Pp1158 antikoerper, ANGPTL4 antikoerper, fiaf antikoerper, im:7144703 antikoerper, si:rp71-39b20.7 antikoerper, angiopoietin like 4 antikoerper, angiopoietin-like 4 antikoerper, ANGPTL4 antikoerper, Angptl4 antikoerper, angptl4 antikoerper

Hintergrund: Synonyms:Angiopoietin like 4, Angiopoietin like protein 4, Angiopoietin related protein 4, ANGPTL2, ANGPTL4, ARP4, FIAF, HFARP, NL2, PGAR, pp1158, PSEC0166, UNQ171/PRO197 Background:Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix(ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation(By similarity).

Molekulargewicht: 45kDa

Gen-ID: 51129

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha