RTEL1 Antikörper

Produktnummer ABIN5700041

Produktdetails anti-RTEL1 Antikörper

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RTEL1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Immunogen: regulator of telomere elongation helicase 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu RTEL1

Target: RTEL1 (Regulator of Telomere Elongation Helicase 1 (RTEL1))

Andere Bezeichnung: RTEL1 (RTEL1 Produkte)

Synonyme: F18B13.3 antikoerper, F18B13_3 antikoerper, C20orf41 antikoerper, DKCB5 antikoerper, NHL antikoerper, RTEL antikoerper, bK3184A7.3 antikoerper, AI451565 antikoerper, AW540478 antikoerper, Rtel antikoerper, RGD1306721 antikoerper, zgc:113114 antikoerper, regulator of telomere elongation helicase 1 antikoerper, RAD3-like DNA-binding helicase protein antikoerper, RTEL1 antikoerper, rtel1 antikoerper, AT1G79950 antikoerper, LOC100286037 antikoerper, Rtel1 antikoerper

Hintergrund: Synonyms:C20orf41, KIAA1088, NHL Background:ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing(SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.

Gen-ID: 51750

UniProt: Q9NZ71