F-Box Protein 3 Antikörper

Produktnummer ABIN5699902

Produktdetails anti-F-Box Protein 3 Antikörper

Target: F-Box Protein 3 (FBXO3)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F-Box Protein 3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Immunogen: F-box protein 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu F-Box Protein 3

Target: F-Box Protein 3 (FBXO3)

Andere Bezeichnung: FBXO3 (FBXO3 Produkte)

Synonyme: FBA antikoerper, FBX3 antikoerper, 1200002G09Rik antikoerper, 1700026K02Rik antikoerper, AI046358 antikoerper, Fba antikoerper, zgc:112485 antikoerper, DKFZp459H187 antikoerper, F-box protein 3 antikoerper, F-box protein 3 S homeolog antikoerper, FBXO3 antikoerper, Fbxo3 antikoerper, fbxo3.S antikoerper, fbxo3 antikoerper

Hintergrund: Synonyms:FBX3 Background:Substrate recognition component of the SCF(SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.

Molekulargewicht: 48-50 kDa

Gen-ID: 26273

UniProt: Q9UK99